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Customer Success Story
Circular RNAs accumulate with age, but how they functionally impact on aging remains elusive. Published in Molecular Cell, RNase k has been discovered as a trash remover to cleave circRNAs aggregated and accumulated in stress granules with aging[1]. Raising RNASEK is necessary and sufficient for longevity, and conversely, reducing it leads to accelerated aging in model systems. Arraystar circular RNA Arrays were used to profile circRNAs in the study.
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Arraystar Circular RNA Arrays
• The only practical platform for highly sensitive and specific circular RNA profiling.
• Circular junction-specific probes, linear RNA removal and efficient circRNA labeling ensure the most specific, accurate and reliable circRNA expression profiling.
• Detailed annotation specific to circRNA biology, e.g. miRNA binding to unravel functional roles as miRNA sponges.
• The preferred choice over RNA-sequencing, due to the particular properties of circular RNA.
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